Clinical Evidence
Need for Early Detection of Asymptomatic Patients for TAVR and SAVR
EARLY TAVR Trial
The EARLY TAVR clinical trial conclusively demonstrated that early intervention for asymptomatic severe aortic stenosis significantly reduces mortality and adverse clinical events compared to surveillance.
However, asymptomatic patients remain unidentified in primary care settings due to:
01
Lack of systematic screening protocols
02
Limited access to specialized diagnostic tools
03
Inefficient screening and referral pathways to cardiology
A distinct heart murmur is often the first sign of aortic stenosis, even in asymptomatic patients.
Symptomatic Patients
Detected
Asymptomatic Patients
Undetected
Transcatheter Aortic Valve Replacement (TAVR)
Surgical Aortic Valve Replacement (SAVR)